Identification, Characterization, and Structure of Tm16 from Trichuris muris

An antagonist of the retinoid X receptor reduces the viability of Trichuris muris in vitro

BACKGROUND Trichuriasis is a parasitic disease caused by the human whipworm, Trichuris trichiura. It affects millions worldwide, particularly in the tropics. This nematode parasite burrows into the colonic epithelium resulting in inflammation and morbidity, especially in children. Current treatment relies mainly on general anthelmintics such as mebendazole but resistance to these drugs is incre...

Characterization of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host–parasite communication

Whipworms are parasitic nematodes that live in the gut of more than 500 million people worldwide. Owing to the difficulty in obtaining parasite material, the mouse whipworm Trichuris muris has been extensively used as a model to study human whipworm infections. These nematodes secrete a multitude of compounds that interact with host tissues where they orchestrate a parasitic existence. Herein w...

Trichuris muris Nematode Parasite Intestine of Mice Infected with the Intestinal and Isolated Lymphoid Follicles in the Large Lymphocytes, Lamina Propria Leukocytes, The Characterization of Intraepithelial

Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris

BACKGROUND Whipworms and blood flukes combined infect almost one billion people in developing countries. Only a handful of anthelmintic drugs are currently available to treat these infections effectively; there is therefore an urgent need for new generations of anthelmintic compounds. Medicinal plants have presented as a viable source of new parasiticides. Ajania nubigena, the Bhutanese daisy, ...

Identification of Mycoplasma Muris Isolated from Vaginal Samples of NIH Mice

Mycoplasma muris (M.M) is a small pathogenic bacterium that lives in the female mouse genital tract. Mycoplasma muris may have harmful effects on the reproductive health of female. This research was performed to optimize the detection of M. muris in NIH mice in the Department of Animal Breeding, Razi Vaccine and Research Institute, Iran. In this cross-sectional study, 29 vaginal samples of NIH ...